Signal detection in pharmacovigilance

National Center for Biotechnology Information , U. A better understanding of the conditions and mechanisms involved in the detection of adverse drug effects may further improve strategies for pharmacovigilance. Supplemental Content Full text links. Stepping up process rigor Our distinct combination of scientific expertise, process rigor and technology innovation delivers consistent, reliable and insightful results. This could be a problem which has never previously been suspected to be associated with the product; or a known event which is now occurring within a patient group for whom it has not been documented before or perhaps occurring with greater frequency than anticipated.