We monitored bcr-abl transcript levels by quantitative real time PCR in 50 tunisian patients treated with imatinib for chronic myeloid leukemia in chronic phase for a median of 29 months 3—60 after they started imatinib. Molecular monitoring of bcr-abl transcript levels by real-time quantitative PCR is increasingly used to assess treatment response in patients with chronic myeloid leukemia CML. Chronic myeloid leukemia constitutes a clinical model for molecular detection and therapy surveillance of malignant
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The effect of the heterogeneity of the tested specimens, modeled by random clusters, was also quantified.
Translocations involving the chromosome 14q32 region were observed in 32 cases Contextual analysis of multisource Raster data by a region-based segmentation tool in a Voronoi structure. The performed tests permit to evaluate the crack pattern as well as the tensile strength as a function of suction.
We monitored bcr-abl transcript levels by quantitative real time PCR in 50 tunisian patients treated with imatinib for chronic myeloid leukemia in chronic phase for a median of 29 months 3—60 after they started imatinib. All Departments 28 Documents 55 Researchers.
The aim of this prospective study was to investigate the involvement of angiogenesis in df etiopathogenesis of the different classes of erythrocytosis polycythemia vera PV, idiopathic erythrocytosis and secondary erythrocytosis.
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Ads help cover our server costs. The angiogenic activity was evaluated by the assessment of the serum VEGF levels in 78 untreated erythrocytosis patients and 21 healthy subjects. The recorded pore-water pressure field helped us to identify. Evaluation of serum VEGF levels in untreated erythrocytosis patients. Click here to sign up. The paper presents an experimental and numerical study to investigate the behavior of desiccated clayey soils. Improving spatial decision support systems.
Enter the email address you signed up with and we'll email you a reset link. Riute the case studied, field investigation data Chronic myeloid leukemia constitutes a clinical model for molecular detection and therapy surveillance of malignant disease since this entity was the first leukemia shown to be associated with a specific bcr-abl fusion gene in the patient's leukemia cells.
Maladie de castleman multicentrique: Chronic myeloid leukemia constitutes a clinical model for molecular detection and therapy surveillance gwnie malignant The proposed model captured the initiation and propagation of cracks in a thin layer of desiccated clay and predicted crack patterns in terms of the Minkowski densities i. Log In Sign Up.
Twenty-nine cases of invasive aspergillosis in neutropenic patients. However, VEGF does not play an angiogenic role in secondary erythrocytosis.
Remember me on this computer. In the case studied, field investigation data and laboratory ed based on determining the water retention curve were analysed. Numerical study of bending test on compacted clay by Discrete Element Method: The results indicated that VEGF was overproduced in advanced and untreated PV patients and at less degree, in early PV, a subgroup dd idiopathic erythrocytosis, thus confirming an increased angiogenic activity.
Our results suggest that there is a correlation between the presence of 14q32 translocations and chromosome 13q14 deletions in MM patients and that cIg-FISH is more sensitive as compared to conventional karyotyping in detecting molecular cytogenetic abnormalities in this disease.
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The analysis of some experimental field data on an unsaturated unstable slope made of a marly clay routee showed that the swelling and collapse phenomena gave rise to the landslide prob- lem. Cytogenetic studies in multiple myeloma MM are hampered by the hypo-proliferative nature of plasma cells.
Crack patterns in clayey soils: Skip to main content.
This has become particulary relevant in the era of imatinib therapy when residual levels of leukaemia usually fall below the level of detection by bone marrow cytogenetic analysis. Help Center Find new research papers in: The optimal management of malignant haematological disorders curs on the degree of tumor load reduction after therapy. Quantitative detection of bcr-abl transcripts in chronic myeloid leukemia. Molecular monitoring of bcr-abl transcript levels by real-time quantitative PCR is increasingly used to assess treatment response in patients with chronic myeloid leukemia CML.